Ceramide is a brown extract refined from rice bran or rice germ. Ceramide contains a large amount of glycophingolipids which are effective antigens and immunogens. Glycophingolipids have been classified as cell surface antigens as binding sites for bacterial toxins and bacterial infection.
Ceramides are contained in the skin and play important roles in maintaining the barrier function and homeostasis of the skin. Ceramides are found to be reduced in the stratum corneum (outermost layer of the skin) of atopic dermatitis, dry skin, and aged persons. Thus, a lack of Ceramide is considered to be a cause of wrinkles and dry skin.